Take a lesson from wood rats: These Southwest U.S. desert dwellers live on toxic plants—and thrive. A 2011 study in Functional Ecology revealed how: When toxins begin to build, wood rats eat less, sample a wider variety of foods, and increase time between meals—all of which lower their overall toxin intake and prevent buildup of any one contaminant. They also drink more water, which flushes out toxins and raises satiety when caloric intake is lower. Smart rodents.