What is in this article?:
- New advice on healthy aging
- Trim calories
- Tame inflammation
- Top Anti-aging Supplements
Here, three longevity luminaries interpret the latest research on how the body ages at a cellular level—and explain how to put this wisdom into action.

Top Anti-aging Supplements
Shore up your defenses against oxidation and inflammation with well-researched vitamin C (500 mg once or twice daily) and vitamin E (400 IU daily), coenzyme Q10 (50 mg once or twice daily), and omega-3 fatty acids such as fish oil (1,000 mg daily). And consider these up-and-coming age-well supplements.
Alpha-lipoic acid (ALA).This antioxidant supports the activity and production of glutathione, the most powerful antioxidant the body makes; consider taking glutathione supplements as well.
Dose: 300 mg daily
Astaxanthin. A potent antioxidant carotenoid found in salmon, krill, algae, and yeast.
Dose: 4 mg twice daily
Curcumin. A promising anti-inflammatory compound derived from the curry spice turmeric.
Dose: 500–750 mg daily
MSM. A type of sulfur, MSM has anti-inflammatory effects. It’s particularly good for alleviating arthritis-related inflammation.
Dose: 1,000–2,000 mg twice daily
N-acetylcysteine (NAC). A primary building block for glutathione, NAC helps boost immunity, detox the liver, and lessen the effects of infections and oxidative stress.
Dose: 250 mg daily
Pterostilbene. Found in blueberries and grapes, this antioxidant has been shown to lower cholesterol and help prevent colon cancer.
Dose: 50 mg once or twice daily
Trans resveratrol. The active part of resveratrol, this antioxidant, anti-inflammatory compound is found in red grape skins and red wine.
Dose: 100–250 mg daily
